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Medchemexpress LLC (E/Z)-GO289 | 694522-87-7 | 99.0% | 419.30 | 5 MG
SDP

Supplier:  Medchemexpress LLC 5MGHY115519

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(E/Z)-GO289 is a potent and selective casein kinase 2 (CK2) inhibitor with an IC50 of 7 nM. It strongly lengthens the circadian period and exhibits cell type-dependent inhibition of cancer cell growth, which correlates with cellular clock function. It has an IC50 of 13 μM for PIM2, which is over 1000 times higher than that for CK2.

  • Potent and selective CK2 inhibitor for modulation of circadian rhythms and cancer cell growth
  • Exhibits cell type-dependent inhibition of cancer cell growth
  • Enables manipulation of clock protein phosphorylation
  • Inhibits Caki-2, A498, and 769-P cells

Catalog No. 50-003-64569


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