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Medchemexpress LLC (E/Z)-Locostatin | 133812-16-5 | 99.5% | 245.27 | 1 ML

Supplier: Medchemexpress LLC HYW01341110MM/1ML
(E/Z)-Locostatin ((E/Z)-UIC-1005) is a racemic form of Locostatin. Locostatin (UIC-1005) is a potent RKIP inhibitor that binds to the Raf kinase inhibitor RKIP protein. It disrupts the interaction of RKIP with Raf-1 kinase and G protein-coupled receptor kinase 2. (E/Z)-Locostatin inhibits cell proliferation and migration and has been shown to aggravate thioacetamide-induced acute liver failure in mice.
- Potent RKIP inhibitor
- Disrupts interaction of RKIP with Raf-1 kinase and G protein-coupled receptor kinase 2
- Inhibits cell proliferation and migration
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