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Medchemexpress LLC E7766 diammonium salt | 2242635-03-4 | 99.48% | 780.66 | 1 MG
Supplier: Medchemexpress LLC 1MGHY111999A
E7766 diammonium salt is a macrocycle-bridged STING agonist with a Kd of 40 nM. It demonstrates potent pan-genotypic and antitumor activities.
- Macrocycle-bridged STING agonist
- Kd of 40 nM
- Shows potent pan-genotypic and antitumor activities
- Inhibits four human STING variants (human wild-type, HAQ, AQ, and REF STING proteins) with EC50 values of 1 μM, 2.2 μM, 1.2 μM, and 4.9 μM, respectively
- Demonstrates potent antitumor activity with a long-lasting immune memory response in a mouse liver metastatic tumor model
- For research use only
- Appearance: Solid
- Color: White to off-white
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