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Medchemexpress LLC E7766 diammonium salt | 2242635-03-4 | 99.5% | 780.66 | 10 MG
Supplier: Medchemexpress LLC HY111999A10MG
E7766 diammonium salt is a macrocycle-bridged STING agonist with a Kd of 40 nM. It demonstrates potent pan-genotypic and antitumor activities. For research use only, not for sale to patients.
- Macrocycle-bridged STING agonist
- Kd of 40 nM
- Potent pan-genotypic activity
- Potent antitumor activities
- Inhibits four human STING variants (human wild-type, HAQ, AQ, and REF STING proteins) with EC50 values of 1 μM, 2.2 μM, 1.2 μM, and 4.9 μM, respectively
- Shows potent antitumor activity with long-lasting immune memory response in a mouse liver metastatic tumor model
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