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Medchemexpress LLC HY-109086 10mg Medchemexpress, Edicotinib CAS:1142363-52-7 Purity:>98%
Supplier: Medchemexpress LLC HY10908610MG
Medchemexpress, HY-109086 10mg Edicotinib CAS:1142363-52-7 Edicotinib (JNJ-40346527; JNJ-527) is a potent, selective, brain penetrant and orally active colony-stimulating factor-1 receptor (CSF-1R) inhibitor with an IC50 of 3.2 nM. Edicotinib (JNJ-40346527; JNJ-527) exhibits less inhibitory effects on KIT and FLT3 with IC50 values of 20 nM and 190 nM, respectively. Edicotinib (JNJ-40346527; JNJ-527) limits microglial expansion and attenuates microglial proliferation and neurodegeneration in mice. JNJ-527 has the potential for alzheimer’s disease and rheumatoid arthritis treatment. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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