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Edvotek™ In Search of Cancer Gene

Students will get to learn the effect of mutations in p53 tumor suppressor gene and its role in familial cancers.

Supplier:  Edvotek™ 314

Catalog No. S11314ND

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Includes: instructions, Ready-to-load™ Predigested DNA samples, UltraSpec-Agarose™ powder, electrophoresis buffer, InstaStain™ Ethidium Bromide, 5 autoradiograms



Suppressor genes such as p53 are essential for cell functions. Mutations in the p53 gene can be correlated to predisposition for certain cancers. Mutations in genes can either be inherited or accumulated due to environmental insults. This experiment deals with a family pedigree determination of several generations relating to cancer formation due to p53 gene mutation. This experiment does not contain human DNA.


Electrophoresis Apparatus
For use students will get to learn the effect of mutations in p53 tumor suppressor gene and its role in familial cancers
Instructions, ready to load, predigested DNA samples, ultraSpec Agarose powder, practice Gel loading solution, electrophoresis Buffer, InstaStain™ Ethidium Bromide, pipet, 5 autoradiograms


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