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Apexbio Technology LLC Efavirenz 154598-52-4 10mM (in 1mL DMSO)
SDP

Supplier:  Apexbio Technology LLC B11195.1

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Efavirenz is a non-nucleoside reverse transcriptase inhibitor targeting human immunodeficiency virus type-1 (HIV-1) reverse transcriptase (RT) It functions by binding specifically to an allosteric site of HIV-1 RT thereby inhibiting viral RNA-dependent DNA polymerase activity essential for HIV replication Efavirenz exhibits inhibitory activity against wild-type HIV-1 RT with reported IC95 values ranging from approximately 1 5 to 3 nM and retains inhibitory potency against several known NNRTI-resistant RT variants Due to its molecular mechanism and specificity Efavirenz is frequently utilized in antiviral studies particularly HIV research investigating RT inhibition and HIV resistance mechanisms

Catalog No. 50-000-61531


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