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Apexbio Technology LLC Efinaconazole 164650-44-6 5mg
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Catalog No. 5000088401
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Efinaconazole (CAS 164650-44-6) is a small-molecule inhibitor targeting the cytochrome P450 enzyme lanosterol 14 -demethylase It is designed to inhibit this enzyme thereby disrupting fungal cell membrane biosynthesis by blocking the conversion of lanosterol to ergosterol Efinaconazole exerts its biological activity primarily through inhibition of lanosterol 14 -demethylase In in vitro studies Efinaconazole demonstrates antifungal activity against dermatophytes implicated in onychomycosis primarily Trichophyton species with an IC50 typically ranging from 0 003 to 0 03 g/mL Based on these pharmacological properties Efinaconazole holds research potential in the evaluation of antifungal efficacy resistance mechanisms and pharmacological profiles relevant to dermatological fungal infections

Catalog No. 50-000-88401 Supplier Apexbio Technology LLC Supplier No. B48345
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Efinaconazole (CAS 164650-44-6) is a small-molecule inhibitor targeting the cytochrome P450 enzyme lanosterol 14 -demethylase It is designed to inhibit this enzyme thereby disrupting fungal cell membrane biosynthesis by blocking the conversion of lanosterol to ergosterol Efinaconazole exerts its biological activity primarily through inhibition of lanosterol 14 -demethylase In in vitro studies Efinaconazole demonstrates antifungal activity against dermatophytes implicated in onychomycosis primarily Trichophyton species with an IC50 typically ranging from 0 003 to 0 03 g/mL Based on these pharmacological properties Efinaconazole holds research potential in the evaluation of antifungal efficacy resistance mechanisms and pharmacological profiles relevant to dermatological fungal infections

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