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Medchemexpress LLC Eg00229 (trifluoroacetate) | 1210945-69-9 | 98.0% | 611.60 g·mol⁻¹ | C19H20F3N7O7S3 | 1 MG
Supplier: Medchemexpress LLC HY107991MG
EG00229 (trifluoroacetate) is a small-molecule antagonist of neuropilin-1 (NRP1) that selectively inhibits VEGF-A binding to the NRP1 b1 domain. It is used as a research reagent to probe NRP1-VEGF signaling, VEGF-A-induced migration, and related cellular responses.
- Selectively inhibits VEGF-A binding to the NRP1 b1 domain with reported IC50 ≈ 3 μM.
- Shows activity in cell-based binding assays (≈8 μM in PAE/NRP1, A549, DU145; ≈23 μM in HUVECs).
- Supplied as the trifluoroacetate salt for improved handling.
- High purity suitable for research applications (≥98% by HPLC).
- Provided with supporting documentation including a product datasheet and safety data sheet.
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