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Medchemexpress LLC Egfr-in-1 Tfa | 2753348-63-7 | 99.4% | 628.60 | 5 MG
SDP

Catalog No. 5000401203
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EGFR-IN-1 TFA is an orally active and irreversible L858R/T790M mutant selective EGFR inhibitor. It potently inhibits Gefitinib-resistant EGFR L858R, T790M with 100-fold selectivity over wild-type EGFR. It exhibits strong antiproliferative activity against H1975 cells and the first-line mutant HCC827 cells, demonstrating antitumor activity.

  • Potently inhibits Gefitinib-resistant EGFR L858R, T790M
  • 100-fold selectivity over wild-type EGFR
  • Strong antiproliferative activity against H1975 cells and HCC827 cells
  • Antitumor activity demonstrated in vivo

Catalog No. 50-004-01203 Supplier Medchemexpress LLC Supplier No. HY19617B5MG
May include imposed supplier surcharges.
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EGFR-IN-1 TFA is an orally active and irreversible L858R/T790M mutant selective EGFR inhibitor. It potently inhibits Gefitinib-resistant EGFR L858R, T790M with 100-fold selectivity over wild-type EGFR. It exhibits strong antiproliferative activity against H1975 cells and the first-line mutant HCC827 cells, demonstrating antitumor activity.

  • Potently inhibits Gefitinib-resistant EGFR L858R, T790M
  • 100-fold selectivity over wild-type EGFR
  • Strong antiproliferative activity against H1975 cells and HCC827 cells
  • Antitumor activity demonstrated in vivo

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