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Medchemexpress LLC Egfr-in-5 | 2225887-26-1 | 99.5% | 571.69 g·mol-1 | C31H38FN9O | 5 MG
SDP

Catalog No. 5000263551
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EGFR-IN-5 is a small-molecule inhibitor of the epidermal growth factor receptor (EGFR) that displays low-nanomolar potency against wild-type EGFR and clinically relevant resistant mutants. It is supplied for research use with confirmed high purity and documented solubility and storage conditions suitable for biochemical and cellular studies.

  • Low-nanomolar inhibitory activity against EGFR and common resistant mutants (IC50: 10.4 nM for wild-type; 1.1 nM for L858R; 34 nM for L858R/T790M; 7.2 nM for L858R/T790M/C797S).
  • High chemical purity suitable for research applications.
  • Soluble in DMSO at ≥ 100 mg/mL; formulation data available for in vivo dosing.
  • Stable as a powder at -20°C for long-term storage; solvent stability documented at -80°C (6 months) and -20°C (1 month).
  • Appropriate for biochemical assays and preclinical cellular studies.

Catalog No. 50-002-63551 Supplier Medchemexpress LLC Supplier No. HY1114155MG
May include imposed supplier surcharges.
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EGFR-IN-5 is a small-molecule inhibitor of the epidermal growth factor receptor (EGFR) that displays low-nanomolar potency against wild-type EGFR and clinically relevant resistant mutants. It is supplied for research use with confirmed high purity and documented solubility and storage conditions suitable for biochemical and cellular studies.

  • Low-nanomolar inhibitory activity against EGFR and common resistant mutants (IC50: 10.4 nM for wild-type; 1.1 nM for L858R; 34 nM for L858R/T790M; 7.2 nM for L858R/T790M/C797S).
  • High chemical purity suitable for research applications.
  • Soluble in DMSO at ≥ 100 mg/mL; formulation data available for in vivo dosing.
  • Stable as a powder at -20°C for long-term storage; solvent stability documented at -80°C (6 months) and -20°C (1 month).
  • Appropriate for biochemical assays and preclinical cellular studies.

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