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Medchemexpress LLC EGFR-IN-70 | 2926716-96-1 | C31H36ClN5O5S | 1 ML
SDP

Supplier:  Medchemexpress LLC HY15061110MM/1ML

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EGFR-IN-70 (compound 18j) is a potent EGFR inhibitor with IC50 values of 23.6 nM for EGFRLR/TM/CS and 307.5 nM for EGFRWT. It exhibits anti-proliferative activity and suppresses the phosphorylation of EGFR. This compound is suitable for cancer research.

  • Potent EGFR inhibitor with IC50 values of 23.6 nM (EGFRLR/TM/CS) and 307.5 nM (EGFRWT)
  • Exhibits anti-proliferative activity
  • Suppresses phosphorylation of the EGFR
  • Suitable for cancer research
  • Demonstrates antiproliferative activity against human A-431 cells (IC50 of 2.003 nM)
  • Exhibits antiproliferative activity against mouse BaF3 cells expressing EGFR L858R/T790M/C797S mutant (IC50 of 0.036 μM)
  • Suppresses phosphorylation of EGFR and downstream signaling ERK level

Catalog No. 50-003-75252


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