Apexbio Technology LLC EGFR Inhibitor 879127-07-8 1mg

Supplier:  Apexbio Technology LLC C33271

EGFR Inhibitor (CAS 879127-07-8) is a cell-permeable pyrimidine small molecule that selectively targets the epidermal growth factor receptor (EGFR) tyrosine kinase By inhibiting EGFR kinase activity with an IC50 of 21 nM this compound disrupts receptor autophosphorylation and downstream signaling It also demonstrates inhibitory activity against EGFR mutants L858R and L861Q with IC50 values of 63 nM and 4 nM respectively Inhibition of EGFR leads to altered expression of apoptotic regulators promoting apoptosis in tumor cells EGFR Inhibitor is valuable for investigating EGFR-dependent cellular processes and mechanisms underlying cancer progression or resistance

Catalog No. 50-000-91473