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Medchemexpress LLC Egfr T790m/L858r-In-2 | 2955607-40-4 | 99.7% | 497.57 | 1 ML
Supplier: Medchemexpress LLC HY14982410MM/1ML
EGFR T790M/L858R-IN-2 is a potent and selective inhibitor of EGFRT790M/L858R, with IC50 values of 3.5 nM for EGFRT790M/L858R and 1290 nM for EGFR WT. It reduces the expression of p-EGFR, P-AKT, and P-ERK1/2, and induces apoptosis and cell cycle arrest in the G1 phase. This compound demonstrates anti-cancer activity. It is intended for research use only and is not sold to patients.
- Potent and selective EGFRT790M/L858R inhibitor
- Reduces expression of p-EGFR, P-AKT, and P-ERK1/2
- Induces apoptosis and cell cycle arrest in G1 phase
- Demonstrates anti-cancer activity
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