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AdipoGen Eicosapentaenoic acid
Supplier: AdipoGen CDXC0465M100
Chemical. CAS 10417-94-4. Formula C20H30O2. MW 302.45. Eicosapentaenoic acid EPA is one of several omega-3 fatty acids abundantly available in marine organisms. EPA has antioxidant, anti-inflammatory, cardiovascular, anticancer and antiobesity activities. EPA is a polyunsaturated fatty acid PUFA that acts as a precursor. When omega-3 fatty acids, like EAP is incorporated into the cell membrane, it induces production of eicosanoids and resolvins which then compete with arachidonic acid for the activity of phospholipase A2. Fatty acids are then liberated inside the cytosol and via cyclooxygenase-2 COX-2, 5-lipoxygenase and thromboxane synthetase activity get degraded into prostaglandins, leukotrienes, and thromboxanes, responsible for decreasing the synthesis of eicosanoids derived from arachidonic acid AA, like PGI2, PGF2alpha, PGE2, and LTB4 pro-inflammatory and increase the synthesis of LT5, thromboxane-3 and PGE3 weak effects on inflammation.
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