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Apexbio Technology LLC Eicosapentaenoyl Serotonin 199875-71-3 5mg (solution)
Supplier: Apexbio Technology LLC C40825
Eicosapentaenoyl serotonin (CAS 199875-71-3) is a synthetic hybrid molecule structurally related to arachidonoyl serotonin which is known to inhibit fatty acid amide hydrolase (FAAH) and antagonize transient receptor potential vanilloid 1 (TRPV1) channels resulting in analgesic effects in rodent studies While the substitution of the arachidonoyl moiety with eicosapentaenoic acid has not yet been characterized analogs with different saturated fatty acid chains displayed potent inhibition of TRPV1 channel activation in capsaicin assays Eicosapentaenoyl serotonin is of interest for investigating novel modulation of pain pathways and TRPV1-mediated signaling
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