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Cayman Chemical eIF2a ActIvatr 2 5mg
Supplier: Cayman Chemical 401305 MG
A TAAR1 agonist increases intracellular cAMP levels in cells expressing TAAR1 (EC50 0.14 UM) an agonist of 5-HT1D and 5-HT1A receptors decreases cAMP levels in cells expressing 5-HT1D and 5-HT1A receptors (EC50s 0.262 and 2.3 UM respectively) selective for these receptors over the dopamine D2L receptor (EC50s 10.44 and 8.02 UM in cAMP and arrestin recruitment assays respectively) as well as a2A- and a2B- adrenergic receptors and 5-HT1B 5-HT2A 5-HT2C and 5-HT7 receptors (EC50s 6.7-10 UM in functional assays) reduces PCP-induced hyperactivity in mice at 0.3 1 and 3 mg/kg increases prepulse inhibition of the acoustic startle response in mice at 3 10 and 30 mg/kg
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