Medchemexpress LLC Ela-32(human) (tfa) | 99.9% | 3967.82 | 1 MG

Supplier:  Medchemexpress LLC HYP2196A1MG

ELA-32(human) TFA is a potent, high affinity apelin receptor agonist with an IC50 of 0.27 nM and a Kd of 0.51 nM. This product does not bind to GPR15 and GPR25. It activates the PI3K/AKT pathway, promoting the self-renewal of hESCs via cell-cycle progression and protein translation. Additionally, it potentiates the TGFβ pathway, priming hESCs toward the endoderm lineage, and stimulates angiogenesis in HUVEC cells.

• Potent, high affinity apelin receptor agonist
• IC50 of 0.27 nM and a Kd of 0.51 nM
• Exhibits no binding to GPR15 and GPR25
• Activates the PI3K/AKT pathway
• Promotes self-renewal of hESCs via cell-cycle progression and protein translation
• Potentiates the TGFβ pathway, priming hESCs toward the endoderm lineage
• Stimulates angiogenesis in HUVEC cells

Catalog No. 50-004-22545