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Medchemexpress LLC Elacestrant dihydrochloride | 1349723-93-8 | 99.5% | 531.56 | 1 ML
Supplier: Medchemexpress LLC HY19822A10MM/1ML
Elacestrant (RAD1901) dihydrochloride is an orally available and selective estrogen receptor degrader (SERD) with IC50s of 48 and 870 nM for ERα and ERβ, respectively. Elacestrant dihydrochloride also can inhibit growth of ER+ breast cancer cell lines in vitro and in vivo.
- Orally available and selective estrogen receptor degrader (SERD).
- Inhibits growth of ER+ breast cancer cell lines in vitro and in vivo.
- Demonstrates antitumor activity in breast cancer xenograft models.
- Induces complete tumor growth inhibition in mice.
- Tumor growth inhibition is maintained for 4 weeks after withdrawal.
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