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Medchemexpress LLC Elacridar hydrochloride | 143851-98-3 | 99.8% | C34H34ClN3O5 | 5 MG
Supplier: Medchemexpress LLC HY508805MG
Elacridar hydrochloride (GF120918A) is an orally active dual-inhibitor of P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP). This compound is used for research to examine the influence of efflux transporters on agent distribution to the brain and for cancer research.
- Orally active P-glycoprotein (P-gp) inhibitor
- Orally active breast cancer resistance protein (BCRP) inhibitor
- Used to examine the influence of efflux transporters on agent distribution to the brain
- Applicable for cancer research
- Inhibits cell viability of 786-O cells in vitro
- Affects P-glycoprotein and ABCG2 protein expression levels in MCF-7 and 786-O cell lines
- Increases ⁹⁹mTc-MIBI intracellular accumulation in MCF-7 and 786-O cell lines
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