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Medchemexpress LLC Eldecalcitol | 104121-92-8 | 99.9% | C30H50O5 | 5 MG
Supplier: Medchemexpress LLC HYA00205MG
Eldecalcitol (ED-71) is an orally active vitamin D3 analogue that inhibits bone resorption and increases bone mineral density. It also exhibits an anti-tumor effect, inhibits cell proliferation, migration, and induces apoptosis by suppressing GPx-1.
- Orally active vitamin D3 analogue
- Inhibits bone resorption and increases bone mineral density
- Exhibits anti-tumor effects
- Inhibits cell proliferation and migration
- Induces apoptosis by suppressing GPx-1
- Shows no cytotoxicity at 0-50 nM for 24 hours
- Reduces cell death induced by LPS
- Inhibits LPS-induced pyroptosis by activating Nrf2 and its effector molecule HO-1
- Arrests cell cycle at G0/G1 phase
- Stimulates focal bone formation and suppresses bone resorption
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