BioVendor, LLC IGFBP-3 Functional Human ELISA (96 wells)

Supplier:  BioVendor, LLC E04A

IGFBP-3 Functional Human LIA, 96 wells. Ligand-binding immunoassay kit to measure functional Insulin-Like Growth Factor Binding Protein-3 in human serum or plasma. Only functional bioactive IGF-I-binding IGFBP3 is quantified, while proteolytic fragments without binding affinity to the natural ligand IGF-I are not. Performance like a conventional ELISA. QC controls included. SAMPLE REQ.: 10 l/well. CAL RANGE: 0.430 ng/ml. ASSAY RANGE: 0.03 15150 ng/mL. DETECTION LIMIT: 0.1 ng/ml. SUMMARY: IGFBP3 proteolysis causes fragmentation and at least partial loss of IGF-I binding affinity. An increase in IGFBP-3 fragmentation is seen in: pregnancy, GH Receptor Insensitivity, Catabolic States like sepsis, traumatic and postoperative states, Non-Insulin-Dependent Diabetes, Burns, cancers, and tumor of the nervous system of children. A decrease in IGFBP-3 fragmentation is seen in the synovial fluid of arthritic patients. NAMES: BP-53, IBP3, IBP-3. Manufactured by Mediagnost GmbH, Germany.

Catalog No. 50-894-006