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Medchemexpress LLC Ellagic acid | 476-66-4 | 99.2% | 100 MG
SDP

Supplier:  Medchemexpress LLC HYB0183100MG

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Ellagic acid is a natural antioxidant that acts as a potent and ATP-competitive inhibitor of CK2 and SHP2, with an IC50 of 40 nM and a Ki of 20 nM. It also blocks other kinases such as LYN, PKA, SYK, GSK3, FGR, and CK1.

  • Potent CK2 inhibitor.
  • Inhibits SHP2.
  • Blocks kinases including LYN, PKA, SYK, GSK3, FGR, and CK1.
  • Shows inhibitory activities against Karpas299, SUDHL1, SR786, and FE-PD cell lines.
  • Exhibits cytotoxic effects on MCF-7 cells after radiation treatment.
  • Reduces MDA brain content and TNF-α levels in rats.
  • Increases brain contents of 5-HT, dopamine, and norepinephrine in rats.
  • Decreases histopathological changes induced by Doxorubicin in rats.

Catalog No. 50-004-05757


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