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Medchemexpress LLC ELN318463 | 851600-86-7 | 99.5% | C19H20BrClN2O3S | 5 MG
Supplier: Medchemexpress LLC HY508825MG
ELN318463 is a selective γ-secretase inhibitor that targets amyloid precursor protein (APP). It exhibits differential inhibition of presenilin (PS1)- and PS2-comprised γ-secretase, showing significantly higher selectivity for PS1. This compound behaves as a classic γ-secretase inhibitor and has been shown to reduce brain Aβ levels in models of Alzheimer's disease.
- Highly selective inhibition of PS1 γ-secretase.
- Demonstrates potent inhibition of Aβ production in cells.
- Shows reduced brain Aβ levels in animal models.
- Possesses characteristics of a classic γ-secretase inhibitor.
- Off-white to light yellow solid appearance.
- Soluble in DMSO.
- Available in various quantities.
- Stable under recommended storage conditions.
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