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Apexbio Technology LLC Eltrombopag Olamine 496775-62-3 50mg
Supplier: Apexbio Technology LLC A338750
Eltrombopag Olamine is an orally bioavailable thrombopoietin receptor (c-mpl) agonist that directly stimulates platelet production through activation of the JAK2/STAT signaling pathway In cellular assays using murine BAF3 cells expressing human thrombopoietin receptor (hTpoR) eltrombopag induced STAT-dependent signaling responses with an EC50 value of approximately 0 27 M This compound promotes differentiation of human CD34 progenitor cells into megakaryocytes capable of platelet production Eltrombopag is commonly applied in hematological research particularly in studies involving thrombocytopenia and thrombopoiesis-related mechanisms
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