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Eurofins Discoverx Embelin, 10 mg. (92-1202)
Supplier: Eurofins Discoverx 921202
Embelin is a natural cell-permeable benzoquinone inhibitor of the X-linked inhibitor of apoptosis (XIAP) protein (IC50=4.1uM), acting as an anti-tumor, anti-inflammatory, and analgesic. Activates caspases, blocks growth, and promotes apoptosis in tumor cells with high levels of XIAP. Also prevents XIAP- and caspase-dependent inflammation, and inhibits IKK, preventing NF-kB activation. Also acts as an agonist for GPR84. Provided as 10 mg of dry powder. These highly purified, pre-validated control ligands have been used to qualify our InCELL Hunter, PathHunter and cAMP Hunter cell lines as well as our Assay Ready Kits. Ligands are conveniently supplied with a recommended reconstitution buffer. For detailed information and product-specific datasheet, visit www.discoverx.com/ligands.
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