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Enzo Life Sciences Embelin (50mg). CAS: 550-24-3
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Supplier:  Enzo Life Sciences BMLCM1250050

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Embelin is a novel cell-permeable inhibitor of XIAP (X-linked inhibitor of apoptosis) which was discovered by screening a library of natural products derived from traditional Chinese medicine. It binds to the XIAP BIR3 domain preventing its binding to and inhibition of caspase-9 and effector caspases. Embelin selectively inhibits cell growth in cancer cells expressing high levels of XIAP (IC50 = 3-6 µM) versus normal cells with low levels of XIAP. Alternative name: Embelic acid. Purity: ≥98% (HPLC). Solubility: Soluble in DMSO (10mg/ml). Long Term Storage: -20°C.

Catalog No. 50-201-0431


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