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Abcam EMD 386088 hydrochloride, 5-HT6 agonist, 50MG

Supplier:  Abcam AB12032850MG

Encompass_Preferred

MW 283.2 Da, Purity >98%. Potent 5-HT6 agonist (IC50 = 7.4 nM in 3H-LSD binding and EC50 = 1.0 nM in a functional cAMP assay). Selective over other 5-HT receptors (IC50 values are 110 (5-HT1D), 180 (5-HT1B), 240 (5-HT2A), 450 (5-HT2C), 620 (5-HT4), 660 (5-HT1A ) and 3000 nM (5-HT7)). Shows moderate affinity at 5-HT3 receptors (IC50 = 34 nM). Impairs memory *in vivo*.

The product is subject to the following: Abcam Restricted Use Statement

Catalog No. 50-270-7671


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