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MilliporeSigma™ Activin A, Human, Recombinant Protein, CHO Cells
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                                Quantity:
                            
                        
                        
                            
                                10 μg
                            
                        
                    Description
Recombinant, human activin A (disulfide-linked homodimer of two 116-amino acid residue βA subunits) expressed in CHO cells. Mature βA-monomer lacks a potential N-linked glycosylation site and has a calculated molecular weight of 13kDa. A member of the TGF-β superfamily that is involved in the negative regulation of B lineage lymphocytes. Shown to play an important role in the regulation of hormonogenesis, cellular homeostasis, and differentiation programs. Reported to inhibit endogenous production of IL-6.
                        
                        
                        
                        
                        
                        
                        
                        
                        
                    
                
                
                    
                
                
    
        
            
            Specifications
Specifications
| Formulation | Lyophilized from sterile filtered 35% acetonitrile, 0.1% TFA, 50μg BSA/μg Activin A. | 
| Preparation Method | Reconstitute to a concentration ≥10μg/mL with sterile PBS containing ≥0.1% HSA or BSA. | 
| Purification Method | SDS-PAGE | 
| Quantity | 10 μg | 
| Immunogen | Activin A | 
| Storage Requirements | Following reconstitution, aliquot and freeze (−70°C). Stock solutions are stable for up to 3 months at −70°C. Avoid freeze/thaw cycles of solutions. | 
| Regulatory Status | RUO | 
| Cell Type | CHO Cells | 
| Species | Human | 
| Recombinant | Recombinant | 
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