MilliporeSigma™ Activin A, Human, Recombinant Protein, CHO Cells

Manufacturer:  MilliporeSigma™ 11470010UG

Catalog No. 11-470-010UG

Description

Recombinant, human activin A (disulfide-linked homodimer of two 116-amino acid residue βA subunits) expressed in CHO cells. Mature βA-monomer lacks a potential N-linked glycosylation site and has a calculated molecular weight of 13kDa. A member of the TGF-β superfamily that is involved in the negative regulation of B lineage lymphocytes. Shown to play an important role in the regulation of hormonogenesis, cellular homeostasis, and differentiation programs. Reported to inhibit endogenous production of IL-6.

Specifications

• Format: Lyophilized
• Preparation Method: Reconstitute to a concentration ≥10μg/mL with sterile PBS containing ≥0.1% HSA or BSA.
• Purity: ≥95%
• Immunogen: Activin A
• Regulatory Status: RUO
• Host Species: Human

• Formulation: Lyophilized from sterile filtered 35% acetonitrile, 0.1% TFA, 50μg BSA/μg Activin A.
• Purification Method: SDS-PAGE
• Quantity: 10μg
• Storage Requirements: Following reconstitution, aliquot and freeze (−70°C). Stock solutions are stable for up to 3 months at −70°C. Avoid freeze/thaw cycles of solutions.
• Cell Type: CHO Cells
• Recombinant: Yes