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MilliporeSigma™ Angiostatin K1-3, Human, Recombinant Protein, E. coli

Catalog No. 176708250UG Shop All MilliporeSigma Products
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17-670-8250UG 250 μg
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Catalog No. 17-670-8250UG Supplier MilliporeSigma™ Supplier No. 176708250UG
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Description

Recombinant, human angiostatin expressed in E. coli as a single, nonglycosylated polypeptide chain containing 259 amino acids. Represents a proteolytic fragment containing the first three kringle structures of plasminogen. Acts as a specific inhibitor of endothelial cell growth and angiogenesis. Displays increased inhibitory activity (ED50=70nM) relative to kringles 1-4 (ED50=135nm).
TRUSTED_SUSTAINABILITY

Specifications

Formulation Lyophilized from 20mM Sodium Acetate, 4% Mannitol, pH 5.5.
Preparation Method H2O or Aqueous Buffer Containing 0.1% BSA
Purification Method HPLC and SDS-PAGE
Quantity 250 μg
Source E. coli
Immunogen Angiostatin K1-3
Storage Requirements Following reconstitution, aliquot and freeze (−20°C). Stock solutions are stable for up to 6 months at −20°C.
Regulatory Status RUO
Species Human
Recombinant Recombinant
Form Lyophilized
Purity or Quality Grade ≥95%
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