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MilliporeSigma™ Calbiochem™ Human Plasma alpha1-Acid Glycoprotein

Native α1-acid glycoprotein from human plasma used for the study of the structure of oligosaccharide units

Manufacturer:  MilliporeSigma™ 1122511MG

Catalog No. 11-225-11MG



. Consists of 40 - 45% carbohydrate. Present in human plasma at concentrations of 55 - 140mg/100 ml. Clinically, α1-AG is an acute-phase reactant that, together with haptoglobin, indicates acute inflammation. Selectively suppresses the augmentation of NK cell activity by IFN-α and IFN-γ. The α1-AG:α1-antitrypsin ratio is useful in diagnosis of liver disease. A sialic acid-deficient α1-AG has been observed in serum or urine of patients with Hodgkin’s disease, psoriatic arthritis, diabetes, and chronic myeloid leukemia. Sialic acid-deficient α1-AG has an affinity for vitamin B12.


Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV


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