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Description
Native cathepsin G from human neutrophil. A serine protease that degrades collagen and proteoglycans. Has been implicated in connective tissue diseases such as emphysema and rheumatoid arthritis. Acts as a potent agonist of human platelet activation leading to their aggregation. Reported to be involved in the activation of pro MMP-2 via mechanism requiring MT1-MMP. Inhibited by chymostatin, DFP, and Z-Phe-CH2Br. Reconstitute in 150mM NaCl, 50mM sodium acetate buffer, pH 5.5.
Specifications
Specifications
| Preparation Method | Reconstitute in 50mM NaOAc and 150mM NaCl, pH 5.5. |
| Purification Method | SDS-PAGE |
| Quantity | 100 mIU |
| Immunogen | Cathepsin G |
| Storage Requirements | Following reconstitution, aliquot and freeze (−70°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 1 week at 4°C or for up to 6 months at −70°C. |
| Regulatory Status | RUO |
| Species | Human |
| Recombinant | Native |
| Form | Lyophilized |
| Purity or Quality Grade | ≥95% |
Product Title
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