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MilliporeSigma™ Coagulation Factor α-XIIa, Human Plasma, Protein

Catalog No. 233493500UG Shop All MilliporeSigma Products
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23-349-3500UG 500 μg
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Catalog No. 23-349-3500UG Supplier MilliporeSigma™ Supplier No. 233493500UG
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Description

Native coagulation factor α-XIIa from human plasma prepared from homogeneous Factor XII using dextran sulfate. Dextran sulfate is removed after activation. α-XIIa is a serine protease responsible for activation of Factor XI to Factor XIa. Factor XIIa and prekallikrein are thought to be involved in a reciprocal activation mechanism whereby Factor XIIa activates prekallikrein to kallikrein, which in turn converts Factor XII to Factor XIIa.
TRUSTED_SUSTAINABILITY

Specifications

Concentration Concentration on Label
Formulation In 150mM NaCl, 4mM sodium acetate buffer, pH 5.3.
Purification Method Homogeneous by SDS-PAGE
Quantity 500 μg
Immunogen Coagulation Factor α-XIIa
Storage Requirements Following initial thaw, aliquot and freeze (−70°C).
Regulatory Status RUO
Species Human
Recombinant Native
Form Liquid
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