Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
MilliporeSigma™ Complement C8, Human, Protein
Click to view available options
Quantity:
250 μg
Description
Native, human C8 complement component. Glycoprotein composed of three non-identical subunits of M.W. 64kDa (α), 64kDa (β), and 22kDa (γ). Present in normal human serum at 55μg/mL. On activation of complement via either the classical or alternative pathway, C5 is cleaved into C5a and C5b fragments. The nascent C5b fragment binds to C6, C7, and C8 resulting in formation of the C5b-8 complex on target surfaces. Each membrane-bound, hydrophobic C5b-8 complex combines with three to six C9 molecules to complete the assembly of the lytic C5b-9 complement membrane attack complex (MAC).

Specifications
Specifications
Concentration | Concentration on Label |
Formulation | In PBS, pH 7.2. |
Purification Method | SDS-PAGE |
Quantity | 250 μg |
Immunogen | Complement C8 |
Storage Requirements | Following initial thaw, aliquot and freeze (−70°C). |
Regulatory Status | RUO |
Species | Human |
Recombinant | Native |
Form | Liquid |
Show More |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction