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MilliporeSigma™ Factor I, Human, Protein

Catalog No. 341280250UG Shop All MilliporeSigma Products
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Quantity:
250 μg

Description

Native factor I from human serum. Glycoprotein composed of two non-identical disulfide-bonded subunits of M.W. of 50kDa (α) and 38kDa (β). Present in normal human serum at about 34μg/mL. A serine protease that requires protein cofactor in order to effect substrate cleavage. Thus, either Factor H or Factor I mediates cleavage of C3b. C4-binding protein or complement receptor CR1 can function as the cofactor required for Factor I-mediated cleavage of C4b.
TRUSTED_SUSTAINABILITY

Specifications

Concentration Concentration on Label
Formulation In PBS, pH 7.2.
Purification Method SDS-PAGE
Quantity 250 μg
Immunogen Factor I
Storage Requirements Following initial thaw, aliquot and freeze (−70°C).
Regulatory Status RUO
Species Human
Recombinant Native
Form Liquid
Purity or Quality Grade ≥95%
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