MilliporeSigma™ Interleukin-10, Human, Recombinant Protein, S. frugiperda

Catalog No.	Quantity
40-770-05UG	5 μg

Catalog No. 40-770-05UG Supplier MilliporeSigma™ Supplier No. 4077005UG

Description

Recombinant, human interleukin-10 expressed in S. frugiperda insect cells. Pleiotropic cytokine that can exert either immunosuppressive or immunostimulatory effects on a variety of cell types. Potent modulator of monocyte/macrophage function. Exhibits anti-inflammatory effects by suppressing macrophage proliferation. Blocks lipopolysaccharide induction of MMP-2 and MMP-9. Known to reduce neuronal degeneration following CNS injury by blocking glutamate-induced caspase-3 activation. Human IL-10 is also active on murine cell lines.

Specifications

• Formulation: Carrier-free.
• Preparation Method: Reconstitute in sterile water or buffer to a final concentration of 0.1-1mg/mL as stock solution. Further dilute in buffer such as PBS, 1% BSA.
• Purification Method: SDS-PAGE
• Quantity: 5 μg
• Source: S. frugiperda
• Immunogen: Interleukin-10
• Storage Requirements: Following reconstitution, aliquot and freeze −70°C. Stock solutions are stable for up to 3 months at −70°C. Avoid freeze/thaw cycles of solutions.
• Regulatory Status: RUO
• Species: Human
• Recombinant: Recombinant
• Form: Lyophilized
• Purity or Quality Grade: ≥95%