MilliporeSigma™ Interleukin-6, Human, Recombinant Protein, E. coli

Description

Recombinant, human, interleukin-6 expressed in E. coli. A prototypic pleiotrophic, pro-inflammatory cytokine that stimulates the production of acute phase proteins by hepatocytes. Also known to induce skeletal muscle protein breakdown. Induces growth and differentiation of B cells, T cells, and hepatocytes. Stimulates growth and inhibits constitutive, protein synthesis-independent apoptosis of murine B cell hybridoma 7TD1. IL-6 is produced by macrophages, endothelial cells, and activated T helper cells. Also considered as a potential marker of adipocyte differentiation. Human IL-6 is active on murine cells.

Specifications

• Formulation: Carrier-free.
• Preparation Method: Reconstitute to 0.1-1.0mg/mL in 100mM acetic acid.
• Purification Method: SDS-PAGE
• Quantity: 10 μg
• Source: E. coli
• Immunogen: Interleukin-6
• Storage Requirements: Following reconstitution, aliquot and freeze (−70°C). Stock solutions are stable for up to 3 months at −70°C. Avoid freeze/thaw cycles of solutions.
• Regulatory Status: RUO
• Species: Human
• Recombinant: Recombinant
• Form: Lyophilized
• Purity or Quality Grade: ≥95%