MilliporeSigma™ Upstate™ JMJD1C, Rabbbit Polyclonal, ChIP Validated Antibody and Primer Set

Catalog No.	Quantity	Conjugate
17-102-62MI	25 Assays	Unconjugated

Catalog No. 17-102-62MI Supplier MilliporeSigma™ Supplier No. 1710262

Description

Rabbit Polyclonal Antibody

Specifically detects JMJD1C Clone: in Chimpanzee, Human, Rabbit, Rhesus Ma samples, and it is validated for Chromatin Immunoprecipitation, Immunocytochemistry, Western Blotting

JMJD1C (jumonji domain-containing protein 1C) is also known as TRIP8 and mutations in this histone demethylase have been linked to certain forms of autism. JMJD1C is also thought to work in reactivating genes in embryonic stem cells, pancreatic islet and gastric cancer. JMJD1C has also been implicated as a gene expression regulator. JMJD1C with WHISTLE have recently been shown to also play a role in mouse testis development. JMJD1C has been identified as a nuclear-receptor coactivator and is a candidate gene for autism.

Specifications

• Antigen: JMJD1C
• Applications: ChIP Assay, Immunocytochemistry, Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Formulation: Anti-JMJD1C (rabbit polyclonal). One vial containing 50μL of purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150mM NaCl and 0.05% sodium azide before the addition of glycerol to 30%. Concentration: 0.7mg/mL. Normal Rabbit IgG. One vial containing 125μg of Rabbit IgG in 125μL of storage buffer containing 0.05% sodium azide. ChIP Primers, human β-globin. One vial containing 75μL of each primer (5μM) specific for the human β-globin promoter. FOR: AGG ACA GGT ACG GCT GTC ATC; REV: TTT ATG CCC AGC CCT GGC TC
• Gene Accession No.: Q15652
• Gene Symbols: TRIP8, RP11-10C13.2, JMJD1C, JHDM2C
• Host Species: Rabbit
• Immunogen: KLH-conjugated linear peptide corresponding to human JMJD1C.
• Purification Method: Affinity Purified
• Quantity: 25 Assays
• Regulatory Status: RUO
• Research Discipline: Epigenetics and Nuclear Function
• Primary or Secondary: Primary
• Gene ID (Entrez): NP_116165
• Includes: This ChIPAb+ JMJD1C -ChIP Validated Antibody and Primer Set conveniently includes the antibody and the specific control PCR primers.
• Target Species: Chimpanzee, Human, Rabbit, Rhesus Monkey
• Content And Storage: -20°C for up to 12 months from date of receipt; Upon first thaw and prior to removing the cap centrifuge the vial and gently mix the solution; Aliquot into microcentrifuge tubes and store at −20°C; Avoid repeated freeze/thaw cycles

For Research Use Only