MilliporeSigma Myeloperoxidase, Human Polymorphonuclear Leukocytes, Protein
Manufacturer: MilliporeSigma 475911100UG
DescriptionNative, human myeloperoxidase from polymorphonuclear leukocytes. A lysosomal enzyme that catalyzes oxidations by hydrogen peroxide, including MPO-chloride-mediated killing of microbes and tumor cells, inactivation of chemotactic factors, and cross-linking of proteins. MPO catalyzes the formation of hypochlorous acid that kills bacteria either by binding the halide ion to intracellular constituents or by oxidation of bacterial lipids and proteins.
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|H2O (volume is lot-specific and can be found on the product label). Further dilute in 100mM NaCl, 50mM sodium acetate, pH 6.0. Enzyme may precipitate out of solution in low ionic strength buffers or in distilled H2O.|
|Lyophilized from 100 to 700mM NaCl, 50mM sodium acetate buffer, pH 6.0.|
|Following reconstitution, aliquot and freeze (−20°C or −70°C). Stock solutions are stable for up to 1 year at −20°C or −70°C.|
|Human Polymorphonuclear Leukocytes|
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