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MilliporeSigma™ Pam3Cys-Ser-(Lys)4, Hydrochloride, Protein

Catalog No. 5063502MG Shop All MilliporeSigma Products
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50-635-02MG 2 mg
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Description

A cell-permeable, water-soluble synthetic cationic lipohexapeptide analog of the immunologically active N-terminal portion of bacterial lipoprotein that potently activates monocytes and macrophages. Induces the release of IL-1, IL-6, TNF-α, superoxide, and NO. Promotes the translocation of NF-κB, enhances tyrosine protein phosphorylation and activation of ERK1/2 and MEK1/2. Acts as a selective agonist of TLR2 (Toll-like receptor 2).
TRUSTED_SUSTAINABILITY

Specifications

Preparation Method H2O (2mg/mL)
Purification Method HPLC
Quantity 2 mg
Immunogen Pam3Cys-Ser-(Lys)4, Hydrochloride
Storage Requirements Following reconstitution, aliquot and freeze (−20°C). Avoid freeze/thaw cycles of solutions.
Regulatory Status RUO
Recombinant Native
Form Lyophilized
Purity or Quality Grade ≥90%
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