MilliporeSigma™ Parathyroid Hormone 1-34, Human, Calbiochem
Supplier: MilliporeSigma™ 052355011MG
DescriptionN-terminal active peptide fragment of the native hormone that functions as a regulatory factor in the homeostatic control of Ca2+ and phosphate metabolism. Regulates Ca2+ and phosphate flux across cellular membranes in bone and kidney, resulting in increased serum Ca2+ levels. Increases the activity of osteoblasts and osteoclasts. Increases tubular reabsorption of Ca2+ and stimulates renal hydroxylation of 25-(OH)-Vitamin D3 to 1,25-(OH)2-Vitamin D3. Increases the production of inhibitory IGF binding protein 4 in bone cells.
|White to Off-white|
|Parathyroid Hormone 1-34|
|RUO - research use only|
|Following reconstitution, aliquot and freeze (−20°C). Stock solutions are stable for up to 3 months at −20°C.|
|Supplied as an acetate salt.|
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