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Medchemexpress LLC EML4-ALK kinase inhibitor 1 | 1373409-08-5 | 98.0% | 580.76 | 10 MG
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Supplier:  Medchemexpress LLC HY11175210MG

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EML4-ALK kinase inhibitor 1 is a potent, orally active inhibitor of echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK), with an IC50 of 1 nM. It is intended for research use only and not for sale to patients.

  • Potent orally active inhibitor of EML4-ALK with an IC50 of 1 nM.
  • IC50 & target: 1 nM (EML4-ALK).
  • Cellular effect (BaF3 cell line): IC50: 1 nM - Inhibition of EML4-fused ALK variant 1 expressed in mouse BAF3 cells.
  • Cellular effect (BaF3 cell line): IC50: 9.7 nM - Antiproliferative activity against mouse BAF3 cells expressing EML4-fused ALK variant 1.

Catalog No. 50-004-36879


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