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Medchemexpress LLC EML4-ALK kinase inhibitor 1 | 1373409-08-5 | 98.0% | 580.76 | 100 MG
Supplier: Medchemexpress LLC HY111752100MG
EML4-ALK kinase inhibitor 1 is a potent orally active inhibitor of echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK), with an IC50 of 1 nM.
- Potent orally active inhibitor of EML4-ALK.
- IC50 of 1 nM against EML4-ALK.
- Inhibits EML4-fused ALK variant 1 in mouse BAF3 cells (IC50 1 nM).
- Exhibits antiproliferative activity against mouse BAF3 cells expressing EML4-fused ALK variant 1 (IC50 9.7 nM).
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