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Medchemexpress LLC Emodin 6-O-β-D-glucoside (Glucoemodin) | 34298-85-6 | 5 MG
Supplier: Medchemexpress LLC HYN81265MG
Emodin-6-O-β-D-glucoside (Glucoemodin) is an active compound derived from Reynoutria japonica. It demonstrates potent anti-inflammatory and barrier protective effects, making it suitable for research into diabetic complications and atherosclerosis.
- does not affect cell viability in HUVECs at concentrations up to 20 μM.
- inhibits high glucose-induced expression of VCAM-1, ICAM-1, and E-selectin.
- reduces high glucose-induced MCP-1 and IL-8 mRNA expression levels.
- decreases THP-1 cell adhesion to high glucose-induced HUVECs.
- significantly inhibits high-glucose-induced ROS formation and p65 NF-κB expression.
- markedly inhibits peritoneal leakage of dye induced by high glucose in mice.
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