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Cayman Chemical EmraclIdIn 50mg
Supplier: Cayman Chemical 4212550 MG
An M4 muscarinic receptor PAM; selective for M4 mAChRs over a panel of 59 receptors, ion channels, transporters, and enzymes at 10 µM; selectively potentiates ACh-induced activation of the M4 mAChR over M1-M3 and M5 mAChRs in cells expressing the human receptors (EC50s = 12.3, 4,798, >10,000, >10,000, and >10,000 nM, respectively); inhibits amphetamine-induced locomotor activity in mice and prepulse inhibition deficits in rats at 3.2 mg/kg
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