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Cayman Chemical Enarodustat 10MG

Supplier: Cayman Chemical 3378510 MG
A pan HIF-PH inhibitor (Kis = 16, 61, and 101 nM for HIF-PH1, -2, and -3, respectively); increases EPO levels in Hep3B cells (EC50 = 4.7 µM); increases plasma EPO levels in control rats, as well as plasma EPO and hemoglobin levels in 5/6-nephrectomized rats at 3 mg/kg; decreases renal fatty acid and amino acid metabolism and increases renal glucose metabolism in streptozotocin-induced rat and alloxan-induced mouse models of diabetic nephropathy
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