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Medchemexpress LLC Enasidenib mesylate | 1650550-25-6 | 99.7% | 569.48 | 1 ML
SDP

Supplier:  Medchemexpress LLC HY18690A10MM/1ML

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Enasidenib mesylate is a first-in-class, oral, potent, reversible, selective inhibitor of the IDH2 mutant enzymes. It is for research use only.

  • Reverses effects of mutant IDH2 on DNA methylation.
  • Induces differentiation and impairs self-renewal of IDH2-mutant leukemia cells.
  • Improves survival in IDH2-mutant acute myeloid leukemia models.
  • Remodels the epigenetic state of IDH2-mutant cells.
  • Reduces 2-HG in vivo and restores differentiation.

Catalog No. 50-003-88079


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