Medchemexpress LLC endo-BCN-PEG4-PFP ester | 2904607-26-5 | 95.0% | 607.56 | 50 MG

Supplier:  Medchemexpress LLC HY14007350MG

endo-BCN-PEG4-PFP ester is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. It functions as a click chemistry reagent, containing a BCN group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules possessing Azide groups. PROTACs are heterobifunctional nanomolecules that comprise two distinct ligands joined by a linker, where one ligand targets an E3 ubiquitin ligase and the other targets a specific protein, leveraging the intracellular ubiquitin-proteasome system for selective protein degradation.

• Functions as a click chemistry reagent
• Contains a BCN group for strain-promoted alkyne-azide cycloaddition (SPAAC)
• Reacts with molecules possessing azide groups
• Utilized in the synthesis of PROTACs
• Leverages the intracellular ubiquitin-proteasome system
• Enables selective degradation of target proteins

Catalog No. 50-003-49857