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Medchemexpress LLC endo-BCN-PEG4-PFP ester | 2904607-26-5 | 95.0% | 607.56 | 50 MG
SDP

Catalog No. 5000349857
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endo-BCN-PEG4-PFP ester is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. It functions as a click chemistry reagent, containing a BCN group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules possessing Azide groups. PROTACs are heterobifunctional nanomolecules that comprise two distinct ligands joined by a linker, where one ligand targets an E3 ubiquitin ligase and the other targets a specific protein, leveraging the intracellular ubiquitin-proteasome system for selective protein degradation.

  • Functions as a click chemistry reagent
  • Contains a BCN group for strain-promoted alkyne-azide cycloaddition (SPAAC)
  • Reacts with molecules possessing azide groups
  • Utilized in the synthesis of PROTACs
  • Leverages the intracellular ubiquitin-proteasome system
  • Enables selective degradation of target proteins

Catalog No. 50-003-49857 Supplier Medchemexpress LLC Supplier No. HY14007350MG
May include imposed supplier surcharges.
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endo-BCN-PEG4-PFP ester is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. It functions as a click chemistry reagent, containing a BCN group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules possessing Azide groups. PROTACs are heterobifunctional nanomolecules that comprise two distinct ligands joined by a linker, where one ligand targets an E3 ubiquitin ligase and the other targets a specific protein, leveraging the intracellular ubiquitin-proteasome system for selective protein degradation.

  • Functions as a click chemistry reagent
  • Contains a BCN group for strain-promoted alkyne-azide cycloaddition (SPAAC)
  • Reacts with molecules possessing azide groups
  • Utilized in the synthesis of PROTACs
  • Leverages the intracellular ubiquitin-proteasome system
  • Enables selective degradation of target proteins

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