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TARGETMOL CHEMICALS INC ENDOSIDIN-2 5MG
SDP

Supplier:  TARGETMOL CHEMICALS INC T37020

Encompass_Preferred

Also available in 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Endosidin-2 is an exocyst inhibitor a cell-permeable benzylidene benzoylhydrazine that binds to the exocyst component of the 70 kDa (EXO70) subunit of the exocyst complex (Kd = 253 uM EXO70A1).Endosidin-2 disrupts protein translocation between the endosomes and plasma membrane thereby facilitating translocation of proteins to the vesicle for degradation. It also inhibits recirculation of endocytosed transferrin to the plasma membrane in HeLa cells and targets multiple isoforms of mammalian EXO70 leading to dysregulation of exocytosis.Endosidin2 can be used as a tool molecule to study cytosolization. purity: 98%

Catalog No. 50-258-0151


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