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Cayman Chemical Endosulfn II 10mg

Supplier: Cayman Chemical 2425410 MG

A potent inhibitor of Cdk1 Cdk2 and Cdk9 (IC50s 16 6 and 20 nM respectively) inhibits kinase activity of Cdk5/p25 and GSK3B induces cell cycle arrest by inhibiting phosphorylation of CDK-dependent substrates has in vivo antiproliferative activity against a range of tumor cell lines (IC50s ranging from 200-1700 nM) in vivo oral administration inhibits growth of human tumor xenografts and inhibits cell cycle proteins
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